Grand Challenges in Global Health initiative

Grand Challenges in Global Health initiative
Unorthodox thinking is essential to overcoming the most persistent challenges in global health. Vaccines were first developed over 200 years ago because revolutionary thinkers took an entirely new approach to preventing disease. Grand Challenges Explorations fosters innovation in global health research. The Bill & Melinda Gates Foundation has committed $100 million to encourage scientists worldwide to expand the pipeline of ideas to fight our greatest health challenges. Launched in 2008, Grand Challenge Explorations grants have already been awarded to 262 researchers from 30 countries. Open to All Disciplines: Anyone Can Apply
The grant program is open to anyone from any discipline, from student to tenured professor, and from any organization – colleges and universities, government laboratories, research institutions, non-profit organizations and for-profit companies.

Agile, Accelerated Grant-Making
The initiative uses an agile, accelerated grant-making process with short two-page applications and no preliminary data required. Applications are submitted online, and winning grants are chosen approximately 4 months from the submission deadline. Initial grants of $100,000 are awarded two times a year. Successful projects have the opportunity to receive a follow-on grant of up to $1 million.
How Grand Challenges Explorations Grants are Selected

Grand Challenges Explorations is a unique initiative that supports innovative research of unorthodox ideas. Every aspect of the program, including the carefully designed topics describing critical scientific barriers to progress in global health, the two-page online application, and the rapid review process, are designed to swiftly award funding to scientists who are testing unproven ideas that could lead to breakthroughs in global health.

As part of an initial review by internal staff, proposals are screened to ensure that they address the scientific barrier described in a topic. Applications that are disqualified at this stage from further review include those that are outside the scope of the topic; those that focus on ideas specifically excluded in the topic description; or those that do not describe a clear and testable hypothesis.
The second step in the review process is among the most unique in scientific grant programs. Our approach to identifying truly creative ideas and novel approaches requires a panel of reviewers with broad expertise and experience in discovering inventive approaches to daunting issues. All applications are sent to the reviewers without applicant details or organizational information.

Proposals are evaluated by some of the world’s leading innovative minds, who are each empowered to select one to two proposals he/she finds most pioneering based on the creativity of the idea and the experimental plan described in the proposal. No consensus is needed for an idea to be awarded a Grand Challenges Explorations grant – it simply needs to be championed by one of these reviewers.
The final step in the review is a rapid due diligence evaluation to ensure that the investigator and institution have the basic institutional capacity to receive the grant and perform the work described.

* Download and read the Rules and Guidelines document (PDF)
* http://www.grandchallenges.org/GCGHDocs/GCEApplication_Form.doc
* Create an account , Register for a Topic, and Submit your Proposal

Moreinfo: http://www.grandchallenges.org/Explorations/Pages/Introduction.aspx