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Tuesday, December 16, 2008

Postgraduate Studentship on The role of hyperactivated motility and fluid mechanics in human fertility - Uiversity of Oxford

Postgraduate Studentship
The role of hyperactivated motility and fluid mechanics in human
fertility

Department of Mathematics
STUDENTSHIP covers fees (University and College) and maintenance.
Applications are invited for a postgraduate studentship, funded by the
King Abdullah University of Science and Technology Global Research
Partnership [KAUST GRP], to work on human sperm dynamics, in particular
"The role of hyperactivated motility and fluid mechanics in human
fertility" under the supervision of Dr Eamonn Gaffney. This DPhil
studentship will start on 1 October 2009, is available to all
nationalities, covers maintenance and full overseas fees and will be
based in the newly established Oxford Centre for Collaborative Applied
Mathematics (OCCAM).

OCCAM has been established with substantial funding from the KAUST GRP.
The Centre, which is part of the Mathematical Institute, will be allied
to a global network of mathematicians. Aiming to meet the
ever-increasing global demand for quantitative understanding of complex
scientific phenomena, OCCAM has been built on the strength of four
pre-existing groups of applied and computational mathematicians working
in Oxford: the Oxford Centre for Industrial and Applied Mathematics, the
Centre for Mathematical Biology, the Numerical Analysis Group and the
Computational Biology Group. It has a symbiotic relationship with other
scientific communities which have a need for problem-solving mathematics
both within the University of Oxford and beyond. Over the first five
years the centre will employ 40 new staff and students.

The accumulation of human sperm cells at boundaries is ubiquitous in the
laboratory setting, and is therefore likely to influence the path of a
sperm during its passage along the female reproductive tract. However,
very little is known about the details of such mechanics especially how
it is affected by surface topographies. This is despite the fact that
sperm have to navigate increasingly convoluted surfaces and folds along
the human fallopian tubes, creating a very complex geometry on the
journey towards an egg. Sperm found in the vicinity of an egg are
hyperactivated, which is characteristed by high amplitude tail beating.
This has led to the hypothesis that hyperactivation is necessary to
prevent excessive sperm trapping within crypts of the fallopian tubes.

Consequently, the initial aim of this project is to use high speed
imaging in the classification of hyperactivated human sperm motility
using kinematic and biophysical parameters. This will require a limited
amount of experimental work in the laboratories of collaborators at The
University of Birmingham. The subsequent aim will be to develop models
of hyperactivated human sperm, using the imaging data to ensure typical
beat patterns are correctly represented. We will then investigate the
mechanisms and mechanics by which sperm progress across convoluted
topographies and escape from fallopian tube crypts. Such studies will
require cutting-edge mathematical and computational modeling in the
areas of low Reynolds number flows and filament-fluid interactions.

The collaborators involved in this project are Professor JR Blake (
Mathematics, University of Birmingham), and Dr J. Kirkman-Brown and Dr
DJ Smith (Clinical and Experimental Medicine, University of Birmingham &
the Centre for Human Reproductive Science, Birmingham Women's NHS
Foundation Trust, U.K.)

The studentship is attached to Brasenose College.

For information about OCCAM please visit our website:
www.maths.ox.ac.uk/occam

Applications can be made online at
www.ox.ac.uk/admissions/postgraduate_courses/apply/how_to_apply.html and
should include a CV, covering letter, three references and a transcript
of your undergraduate degree. Alternatively, applications can be sent to
Margret Sloper at the Mathematical Institute using the University's
application form for graduate study, which can be downloaded from the
above link. Applications must arrive by end of day Friday 27th February
2009. The reference for this application is BK/08/059; make sure that
you state this in the covering letter. Applicants must arrange for their
referees to send references directly to the Graduate Studies Assistant
(fax or e-mail is sufficient) by the closing date. For further details
about the projects, including the application process, please see the
Further Particulars link below, or contact Graduate Studies, email
graduate.studies@maths.ox.ac.uk

Oxford University is an Equal Opportunity Employer.

The way to AMINEF in Gedung Balai Pustaka

American Indonesian Exchange Foundation
Balai Pustaka Building, 6th. Floor
Jl. Gunung Sahari Raya No. 4
Jakarta 10720, Indonesia

1. The buses which goes to Senen Bus Station all of them pass through Gedung Balai Pustaka. Especially which route is through Pasar Baru .

2. Bus Transjakarta, from Blok M you have to change the bus 2-3 times.
Way 1 : from Blok M change the bus in Dukuh Atas bus stop to the bus towards Pulogadung, then take a bus in Pramuka bus stop towards Ancol, this bus pass through Gedung Balai Pustaka. The closest bus stop (Budi Utomo) is about 800 meters from Gedung Balai .
Way 2 : From Blok M take the bus in the Harmoni Bus Stop, the bus towards Pulogadung, get down in Senen Bus Stop and walk about 800 meters, or from this bus stop take the bus towards Ancol and get down as mentioned in way 1. About the distance, this two bus stops is about the same. (It is better if you take ojek or bajaj from this bus stop to Gedung Balai Pustaka)

3. If you take taxi with old tariff (TL=Tarif Lama) from blok M with no traffic jam is about Rp. 30.000,00.

4. From Blok M use bus Patas AC 76. Gedung Balai Pustaka is in the right side, after you pass through Depag, and say to conductor "Balai Pustaka"

5. Use a busway from Blok M towards Kota, get down in Sawah Besar bus stop. From here take a Mikrolet M12 towards Senen. After cross road Wahidin and before senen get down and cross the street.

Living Cost in Germany

Living Cost in Germany is vary from city to city, but this is th case if you stay in Aachen, Germany
Student accommodation or private sharing : 180 - 230 euros per month
Food : 10 - 12 euros per day (if eating outside)
Transport for students : free within Aachen and until Koln and Dusseldorf in regional trains)

Living Cost In Austria

Living Cost in Austria is depending on the city, for example the Capital of Austria, Vienna:
- Dormitory is about 250-400 euro per month.
- Living Cost 200-400 euro per month.
- Transportation 128 euro per 4 months (student and age < 26), or 49 euro per month (ordinary)

For visa, it has to be a letter from the University/Scholl in Austria. It takes about 2-3 months.

Where to do GMAT Test

GMAT Tests are held in Jakarta, Indonesia :
1. EEC Slipi +62-21 5320044 or +62-215323176
2. Kaplan GMAT Preparation +62-81388908450, +62-21 5211588, +62-215211701 (Information abaout this test can be asked in that number)
3. Or this number +62-213159225

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